@inbook {18239,
	title = {Biomimetic strategies incorporating enzymes into CaP coatings mimicking the in vivo environment.},
	booktitle = {Biomimetics and Stem cells - Methods in Molecular Biology},
	volume = {1202},
	year = {2014},
	month = {2014-12-01 00:00:00},
	pages = {111-119},
	publisher = {Springer},
	organization = {Springer},
	edition = {1},
	abstract = {

Biomimetic calcium phosphate coating (CaP) methodology mimics the natural biomineralization process of bone, which involves two phases: nucleation and growth. In this chapter we present a successful method to coating biodegradable natural-origin materials with biomimetic CaP layer as a strategy to incorporate enzymes with the main aim of controlling and tailoring their degradation over time. This strategy seems to enhance the bone-bonding, osteoconductive, and osteoinductive properties of natural-origin biomaterials that per se do not present these characteristics.

}, keywords = {Biomimetics, CaP coatings, enzymes, Natural-origin biomaterials}, isbn = {978-1-4939-1331-2}, doi = {10.1007/7651_2013_53}, url = {http://link.springer.com/protocol/10.1007\%2F7651_2013_53}, author = {Martins, A. M. and Reis, R. L.}, editor = {Vunjak-Novakovic, G. and Turksen, K.} }

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