@inbook {18883,
	title = {Gene Therapy, Growth Factors, Mesenchymal Cells, New Trends and Future Perspective},
	booktitle = {Surgery of the Meniscus},
	year = {2016},
	month = {2016-03-30 00:00:00},
	pages = {559-575},
	publisher = {Springer International Publishing AG},
	organization = {Springer International Publishing AG},
	abstract = {

Meniscal tears are common, prevalent intra-articular knee injury and the most frequent cause of orthopedic surgical procedures [1], being a significant risk factor for the development of osteoarthritis (OA) [2]. As widely documented in the previous chapters, tears in the peripheral (vascularized) portion of the meniscus can be repaired using a variety of operative procedures, while those in the central (avascular) area have a poorer healing capacity. Reconstruction of a torn meniscus in this location is challenging, and the long-term effect of allografts on the progression of OA remains uncertain [3].

}, keywords = {gene therapy, growth factors, Mesenchymal Cells}, isbn = {978-3-662-49188-}, doi = {10.1007/978-3-662-49188-1_58}, url = {http://link.springer.com/chapter/10.1007/978-3-662-49188-1_58}, author = {Zaffagnini, S. and Cucchiarini, M. and de Girolamo, L. and Angele, P. and Pereira, H. and Reis, R. L. and Madry, H. and Orfei, P. C. and Zellner, J. and Filardo, G.}, editor = {Pereira, H. and Giuseppe, P. and Denti, M.} }

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