Biomaterials, Biodegradables and Biomimetics Research Group

Conference Abstract -ISI Web of Science Indexed

Acellular bilayered scaffolds for osteochondral tissue regeneration

Abstract

Last decade 9.6% of the men and 18% of the woman with more than 60 years presented symptomatic Osteoarthritis [1]. Despite the progress already achieved in osteochondral (OC) repair, some limitations still needs to be overcome. A promising strategy includes a scaffold presenting two regions with different physical characteristics. The use of an acellular structure capable of recruiting the cells during the in vivo OC repair could be a faster and more efficient approach to translate  into the clinics. This work aims to develop bilayered gellan gum (GG)/gellan gum-hydroxyapatite (HAp) freeze-dried scaffolds for OC regeneration.

Journal
Journal of Tissue Engineering and Regenerative Medicine
Volume
8
Pagination
323
Keywords
Acellular, Bilayered Scaffold, In Vivo Inflamation, Osteochondral
Rights
Restricted Access
Peer Reviewed
Yes
Status
published
Project
OsteoCart
Year of Publication
2014
Date Published
2014-06-10
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