Biomaterials, Biodegradables and Biomimetics Research Group

Abstract

Osteoarthritis (OA) affects a large number of the population, and its incidence is showing a growing trend with the increasing life span. OA is the most prevalent joint condition worldwide, and currently, there is no functional cure for it. This review seeks to briefly overview the management of knee OA concerning standardized pharmaceutical and clinical approaches, as well as the new biotechnological horizons of OA treatment. The potential of biomaterials and state of the art of advanced therapeutic approaches, such as cell and gene therapy focused primarily on cartilage regeneration are the main subjects of this review. Biotechnol. Bioeng. 2016;9999: 1-23. © 2016 Wiley Periodicals, Inc.

Journal
Biotechnology and Bioengineering
Volume
114
Issue
4
Pagination
717–739
Publisher
John Wiley & Sons, Ltd
ISSN
1097-0290
URL
http://onlinelibrary.wiley.com/doi/10.1002/bit.26182/abstract
Keywords
articular cartilage, Biomaterials, gene therapy, Osteoarthritis, regeneration, scaffolds, Tissue engineering, viscosupplementation
Rights
Closed Access
Peer Reviewed
Yes
Status
published
Year of Publication
2017
DOI
10.1002/bit.26182
Date Published
2017-02-02
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