Management of knee osteoarthritis. Current status and future trends.

last updated: 2016-10-07
TitleManagement of knee osteoarthritis. Current status and future trends.
Publication TypeReview Paper
Year of Publication2016
AuthorsOndrésik, M., Maia F. R., da Silva Morais A., Gertrudes A., Bacelar A. H., Correia C., Gonçalves C., Radhouani H., Sousa, R.A., Oliveira J. M., and Reis R. L.
Abstract Text

Osteoarthritis (OA) affects a large number of the population, and its incidence is showing a growing trend with the increasing life span. OA is the most prevalent joint condition worldwide, and currently, there is no functional cure for it. This review seeks to briefly overview the management of knee OA concerning standardized pharmaceutical and clinical approaches, as well as the new biotechnological horizons of OA treatment. The potential of biomaterials and state of the art of advanced therapeutic approaches, such as cell and gene therapy focused primarily on cartilage regeneration are the main subjects of this review. Biotechnol. Bioeng. 2016;9999: 1-23. © 2016 Wiley Periodicals, Inc.

JournalBiotechnology and Bioengineering
Pagination1-23
Date Published2016-10-05
PublisherWiley Periodicals, Inc.
ISSN2761-8194
DOI10.1002/bit.26182
URLhttp://onlinelibrary.wiley.com/doi/10.1002/bit.26182/abstract
Keywordsarticular cartilage, Biomaterials, gene therapy, Osteoarthritis, regeneration, scaffolds, Tissue engineering, viscosupplementation
RightsclosedAccess
Peer reviewedno
Statuspublished

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