@article {19976,
	title = {In vitro and In vivo assessments of an optimal polyblend composition of polycaprolactone/gelatin nanofibrous scaffolds for achilles tendon tissue engineering},
	journal = {Journal of Industrial and Engineering Chemistry},
	volume = {76},
	year = {2019},
	month = {2019-03-27 00:00:00},
	pages = {173-180},
	publisher = {Elsevier},
	abstract = {
In this study, we manufactured various ratios of polycaprolactone (PCL)/gelatin (GE) highly aligned electrospun nanofibrous scaffolds (ENs) to investigate the effects of polymer ratio on tenogenic differentiation activity. For biological assessments, the cell proliferation rate was optimal in the PCL/GE (9:1) group. Interestingly, however, the tenogenic differentiation rate was best for the PCL/GE (7:3) group. From our outcomes, we established that a poly-blending mix of PCL/GE (7:3) is a promising ratio for tenogenic differentiation. Thus, our findings may provide for an effective mesh to promote tenogenic differentiation of ENs in future tendon tissue engineering applications.
},
	keywords = {Electrospinning, Gelatin, Highly aligned nanofiber, polycaprolactone, Tendon tissue engineering applications},
	issn = {1226-086X},
	doi = {10.1016/j.jiec.2019.03.036},
	url = {https://www.sciencedirect.com/science/article/pii/S1226086X19301236},
	author = {Lee, S. J. and Kim, H. - J. and Heo, M. and Lee, H. - R. and Choi, E. - J. and Kim, H. and Lee, D. and Reis, R. L. and Do, S. H. and Kwon, I. K.}
}