Book (1)
Papers in Scientific Journals (53)
Matias R. S., Gregory S., Ceia F. R., Baeta A., Seco J., Rocha M. S., Fernandes E. M., Reis R. L., Silva T. H., Pereira E., Piatkowski U., Ramos J. A., and Xavier J. C.,
"Show your beaks and we tell you what you eat: Different ecology in sympatric Antarctic benthic octopods under a climate change context",
Marine Environmental Research, vol. 150, pp. 104757, doi:
10.1016/j.marenvres.2019.104757, 2019.
Costa R. R., González-Pérez M., Herrero-Gutiérrez M., Pires R. A., Alonso M., Rodríguez-Cabello J. C., Reis R. L., and Pashkuleva I.,
"Tuning the stiffness of surfaces by assembling genetically engineered polypeptides with tailored amino acid sequence",
Biomacromolecules, vol. 19, issue 8, pp. 3401–3411, doi:
10.1021/acs.biomac.8b00723, 2018.
Miranda M. S., Rodrigues M. T., Domingues R. M. A., Costa R. R., Paz E., Rodríguez-Abreu C., Freitas P., Almeida B. G., Carvalho M. A., Gonçalves C., Ferreira C. M., Torrado E., Reis R. L., Pedrosa J., and Gomes M. E.,
"Development of Inhalable Superparamagnetic Iron Oxide Nanoparticles (SPIONs) in Microparticulate System for Antituberculosis Drug Delivery",
Advanced Healthcare Materials, vol. 7, issue 15, pp. 1800124, doi:
10.1002/adhm.201800124, 2018.
Carvalho C. R., Wrobel S., Meyer C., Branderberger C., Cengiz I. F., López-Cebral R., Silva-Correia J., Ronchi J., Reis R. L., Grothe C., Oliveira J. M., and Haastert-Talini K.,
"Gellan Gum-based luminal fillers for peripheral nerve regeneration: an in vivo study in the rat sciatic nerve repair model",
BIOMATERIALS SCIENCE, vol. 6, issue 6, pp. 1059-1075, doi:
10.1039/c7bm01101f, 2018.
Silva J. M., Rodrigues, L.C., Silva S. S., Reis R. L., and Duarte A. R. C.,
"Engineered tubular structures based on chitosan for tissue engineering applications",
Journal of Biomaterials Applications, pp. 1-12, doi:
10.1177/0885328217744698, 2017.
Valcarcel J., Novoa-Carballal R., Pérez-Martín R. I., Reis R. L., and José V. A.,
"Glycosaminoglycans from marine sources as therapeutic agents",
Biotechnology Advances, vol. 35, issue 6, pp. 711-725, doi:
10.1016/j.biotechadv.2017.07.008, 2017.
Chen D., Yin Z., Wu F., Fu H., Kundu S. C., and Lu S.,
"Orientational behaviors of silk fibroin hydrogels",
Journal Of Applied Polymer Science, vol. 132, issue 32, doi:
10.1002/app.45050, 2017.
Pereira A. M., Machado R., Costa A., Ribeiro A., Bernardo T. C., Collins T., Gomes A. C., Leonor I. B., Kaplan D. L., Reis R. L., and Casal M.,
"Silk-based biomaterials functionalized with fibronectin type II promotes cell adhesion",
Acta Biomaterialia, vol. 47, issue 1, pp. 50-59, doi:
10.1016/j.actbio.2016.11.008, 2017.
Carvalho C. R., López-Cebral R., Silva-Correia J., Silva J. M., Mano J. F., Silva T. H., Freier T., Reis R. L., and Oliveira J. M.,
"Investigation of Cell Adhesion in Chitosan Membranes for Peripheral Nerve Regeneration",
Materials Science & Engineering C-materials For Biological Applications, vol. 71, pp. 1122-1134, doi:
10.1016/j.msec.2016.11.100, 2017.
Duarte A. R. C., Maniglio D., Sousa N., Mano J. F., Reis R. L., and Migliaresi C.,
"From honeycomb- to microsphere-patterned surfaces of poly(lactic acid) and a starch-poly(lactic acid) blend via the breath figure method",
Journal of Applied Biomaterials & Functional Materials, vol. 15, issue 1, pp. e31-e42, doi:
10.5301/jabfm.5000281, 2017.
Agnello S., Gasperini L., Reis R. L., Mano J. F., Pitarresi G., Palumbo F. S., and Giammona G.,
"Microfluidic production of hyaluronic acid derivative microfibers to control drug release",
Materials Letters, vol. 182, pp. 309-313, doi:
10.1016/j.matlet.2016.07.014, 2016.
Faia-Torres A. B., Charnley M., Goren T., Guimond-Lischer S., Rottmar M., Maniura-Weber K., Spencer N. D., Reis R. L., Textor M., and Neves N. M.,
"Osteogenic differentiation of human mesenchymal stem cells in the absence of osteogenic supplements: a surface-roughness gradient study.",
Acta Biomaterialia, vol. 28, pp. 64-75, doi:
10.1016/j.actbio.2015.09.028, 2015.
Caridade S. G., Monge C., Almodóvar J., Guillot R., Lavaud J., Josserand V., Coll J. - L., Mano J. F., and Picart C.,
"Myoconductive and osteoinductive free-standing polysaccharide membranes",
Acta Biomaterialia, vol. 15, pp. 139-149, doi:
10.1016/j.actbio.2014.12.027, 2015.
Quraishi S., Martins M., Barros, A. A., GuriKov P., Raman S. P., Smirnova I., Duarte A. R. C., and Reis R. L.,
"Novel non-cytotoxic alginate–lignin hybrid aerogels as scaffolds for tissue engineering",
The Journal of Supercritical Fluids, vol. 105, pp. 1-8, doi:
10.1016/j.supflu.2014.12.026, 2015.
Faia-Torres A. B., Goren T., Ihalainen T. O., Guimond-Lischer S., Charnley M., Rottmar M., Maniura-Weber K., Spencer N. D., Reis R. L., Textor M., and Neves N. M.,
"Regulation of Human Mesenchymal Stem Cell Osteogenesis by Specific Surface-Density of Fibronectin: a Gradient Study",
ACS Applied Materials & Interfaces, vol. 7, issue 4, pp. 2367-2375, doi:
10.1021/am506951c, 2014.
Ferreira C. S., Caridade S. G., Mano J. F., and Alves N. M.,
"Homogeneous poly (Lactic acid)/chitosan blended films",
Polymers for Advanced Technologies, vol. 25, issue 12, pp. 1492-1500, doi:
10.1002/pat.3391, 2014.
Costa A. M. S., Alatorre-Meda M., Oliveira N. M., and Mano J. F.,
"Biocompatible polymeric microparticles produced by a simple biomimetic approach",
Langmuir, vol. 30, issue 16, pp. 4535–4539, doi:
10.1021/la500286v, 2014.
Costa R. R., Girotti A., Santos M., Arias F. J., Mano J. F., and Rodríguez-Cabello J. C.,
"Cellular Uptake of Multilayered Capsules Produced with Biomimetic and Genetically Engineered Macromolecules",
Acta Biomaterialia, vol. 10, issue 6, pp. 2653-2662, doi:
10.1016/j.actbio.2014.02.020, 2014.
Rodríguez-Velázquez E.;, Silva M.;, Taboada P., Mano J. F., Suárez-Quintanilla D., and Alatorre-Meda M.,
"Enhanced Cell Affinity of Chitosan Membranes Mediated by Superficial Cross-Linking: A Straightforward Method Attainable by Standard Laboratory Procedures",
Biomacromolecules, vol. 15, pp. 291-301, doi:
dx.doi.org/10.1021/bm401541v, 2013.
Lima A. C., Correia C. R., Oliveira M. B., and Mano J. F.,
"Sequential ionic and thermogelation of chitosan spherical hydrogels prepared using superhydrophobic surfaces to immobilize cells and drugs",
Journal of Bioactive and Compatible Polymers, vol. 29, issue 1, pp. 50-65, doi:
10.1177/0883911513513660, 2013.
Costa-Pinto A. R., Vargel I., Tuzlakoglu K., Correlo V. M., Sol P. C., Faria S., Piskin E., Reis R. L., and Neves N. M.,
"Influence of scaffold composition over in vitro osteogenic differentiation of hBMSCs and in vivo inflammatory response.",
Journal of Biomaterials Applications, vol. 28, issue 9, pp. 1430-1442, 2013.
Costa R. R., Testera A. M., Arias F. J., Rodríguez-Cabello J. C., and Mano J. F.,
"Layer-by-Layer Film-Growth Using Polysaccharides and Recombinant Polypeptides: A Combinatorial Approach",
The Journal of Physical Chemistry B, vol. 117, issue 22, pp. 6839-6848, doi:
10.1021/jp4028518, 2013.
Caridade S. G., Monge C., Gilde F., Boudou T., Mano J. F., and Picart C.,
"Free-standing polyelectrolyte membranes made of chitosan and alginate",
Biomacromolecules, vol. 14, issue 5, pp. 1653-1660, doi:
10.1021/bm400314s, 2013.
Costa R. R., Custódio C. A., Arias F. J., Rodríguez-Cabello J. C., and Mano J. F.,
"Nanostructured and thermoresponsive recombinant biopolymer-based microcapsules for the delivery of active molecules",
Nanomedicine: Nanotechnology, Biology and Medicine, vol. 9, issue 7, pp. 895-902, doi:
10.1016/j.nano.2013.01.013, 2013.
Duarte A. R. C., Santo V. E., Alves A., Silva S. S., Moreira-Silva J., Silva T. H., Marques A. P., Gomes M. E., Sousa R. A., Mano J. F., and Reis R. L.,
"Unleashing the potential of supercritical fluids for polymer processing in tissue engineering and regenerative medicine",
The Journal of Supercritical Fluids, vol. 79, pp. 177-185, doi:
10.1016/j.supflu.2013.01.004, 2013.
Mendes A. C., Baran E. T., Lisboa P., Reis R. L., and Azevedo H. S.,
"Microfluidic Fabrication of Self-Assembled Peptide-Polysaccharide Microcapsules as 3D Environments for Cell Culture",
BIOMACROMOLECULES, vol. 13, issue 12, pp. 4039-4048, doi:
10.1021/bm301332z , 2012.
Mota J., Yu N., Caridade S. G., Luz G. M., Gomes M. E., Reis R. L., Jansen J. A., and Walboomers X. F.,
"Chitosan/bioactive glass nanoparticle composite membranes for periodontal regeneration",
Acta Biomaterialia, vol. 8, issue 11, pp. 4173-4180, doi:
10.1016/j.actbio.2012.06.040, 2012.
Boccaccini A. R., Mano J. F., del Campo A., and Verne E.,
"Materials for Healthcare Applications Symposium, EUROMAT 2011 (Montpellier, France, 12–15 September 2011)",
Biomedical Materials, vol. 7, issue 5, doi:
10.1088/1748-6041/7/5/050201, 2012.
Correia C., Pereira A. L., Duarte A. R. C., Frias A. M., Pedro A. J., Oliveira J. T., Sousa R. A., and Reis R. L.,
"Dynamic culturing of cartilage tissue: the significance of hydrostatic pressure",
Tissue Engineering Part A, vol. 18, issue 19-20, pp. 1979-1991, doi:
10.1089/ten.TEA.2012.0083, 2012.
Caridade S. G., Merino E. G., Alves N. M., and Mano J. F.,
"Bioactivity and viscoelastic characterization of chitosan/Bioglass® composite membranes",
Macromolecular Bioscience, vol. 12, issue 8, pp. 1106-1113, doi:
10.1002/mabi.201200036, 2012.
Gomes S., Leonor I. B., Mano J. F., Reis R. L., and Kaplan D. L.,
"Natural and genetically engineered proteins for tissue engineering",
Progress in Polymer Science, vol. 37, issue 1, pp. 1–17, doi:
10.1016/j.progpolymsci.2011.07.003 , 2012.
Costa R. R., Custódio C. A., Arias F. J., Rodríguez-Cabello J. C., and Mano J. F.,
"Layer-by-Layer Assembly of Chitosan and Recombinant Biopolymers into Biomimetic Coatings with Multiple Stimuli-Responsive Properties",
Small, vol. 7, issue 18, pp. 2640-2649, doi:
10.1002/smll.201100875, 2011.
Neto A. I., Custódio C. A., Song W., and Mano J. F.,
"High-throughput evaluation of interactions between biomaterials, proteins and cells using patterned superhydrophobic substrates",
Soft matter, vol. 7, issue 9, pp. 4147-4151, 2011.
Costa R. R., Custódio C. A., Testera A. M., Arias F. J., Rodríguez-Cabello J. C., Alves N. M., and Mano J. F.,
"Stimuli-Responsive Thin Coatings Using Elastin-Like Polymers for Biomedical Applications",
Advanced Functional Materials, vol. 19, issue 20, pp. 3210-3218, doi:
10.1002/adfm.200900568, 2009.
Barbosa J. S., Costa R. R., Alonso M., Rodríguez-Cabello J. C., and Mano J. F.,
"Multi-Layered Films Containing a Biomimetic Stimuli-Responsive Recombinant Protein",
Nanoscale Research Letters, vol. 4, issue 10, pp. 1247-1253, doi:
10.1007/s11671-009-9388-5, 2009.
Mano J. F., Sousa R. A., Boesel L. F., Neves N. M., and Reis R. L.,
"Bioinert, biodegradable and injectable polymeric matrix composites for hard tissue replacement: state of the art and recent developments",
Composites Science and Technology, vol. 64, issue 6, pp. 789-817, 2008.
Neves N. M., Campos R., Pedro A. J., Cunha J., Macedo F., and Reis R. L.,
"Patterning of polymer nanofiber meshes by electrospinning for biomedical applications.",
Nanomedicine, vol. 2, pp. 433-448, 2007.
Azevedo H. S., Leonor I. B., Alves C. M., and Reis R. L.,
"Incorporation of proteins and enzymes at different stages of the preparation of calcium phosphate coatings on a degradable substrate by a biomimetic methodology",
Materials Science & Engineering C-Biomimetic and Supramolecular Systems, vol. 25, issue 2, pp. 169-179, doi:
10.1016/j.msec.2005.01.007, 2005.
Book Chapter (12)
Oliveira E. P., Silva-Correia J., Reis R. L., and Oliveira J. M.,
"Biomaterials Developments for Brain Tissue Engineering",
Cutting-Edge Enabling Technologies for Regenerative Medicine,
Eds. Chun H. J., Park C. H., Kwon I. K., and Khang G.,
Springer Singapore, 1, vol. 1078, pp. 323-346, doi:
10.1007/978-981-13-0950-2_17, 2018.
da Silva Morais A., Oliveira J. M., and Reis R. L.,
"Small Animal Models",
Osteochondral Tissue Engineering: Challenges, Current Strategies, and Technological Advances,
Eds. Oliveira J. M., Pina S., Reis R. L., and San-Román J.,
Springer, Cham, vol. 1059, pp. 423-439, doi:
10.1007/978-3-319-76735-2_19, 2018.
Gonçalves C., Radhouani H., Reis R. L., and Oliveira J. M.,
"Advances in Biomaterials for the Treatment of Articular Cartilage Defects",
Regenerative Strategies for the Treatment of Knee Joint Disabilities,
Eds. Oliveira J. M., and Reis R. L.,
Springer, vol. 21, pp. 97-126, doi:
10.1007/978-3-319-44785-8_6, 2016.
da Silva Morais A., Oliveira J. M., and Reis R. L.,
"Cartilage Tissue Engineering and Regenerative Strategies",
Regenerative Strategies for the Treatment of Knee Joint Disabilities,
Eds. Oliveira J. M., and Reis R. L.,
Springer International Publishing, vol. 21, pp. 73-96, doi:
10.1007/978-3-319-44785-8_5, 2016.
Oliveira I. M., Gonçalves C., Oliveira J. M., and Reis R. L.,
"Synovial Knee Joint",
Regenerative Strategies for the Treatment of Knee Joint Disabilities,
Eds. Oliveira J. M., and Reis R. L.,
Springer, vol. 21, pp. 21-28, doi:
10.1007/978-3-319-44785-8_2, 2016.
Leonor I. B., Rodrigues A. I., and Reis R. L.,
"Designing biomaterials based on biomineralization for bone repair and regeneration",
Biomineralization and Biomaterials: Fundamentals and Applications,
Eds. Aparicio C., and Ginebra M. P.,
Woodhead Publishing, 1, pp. 377-404, doi:
10.1016/B978-1-78242-338-6.00014-4, 2015.
Rodrigues M. T., Carvalho P. P., Gomes M. E., and Reis R. L.,
"Biomaterials in pre-clinical approaches for Engineering Skeletal Tissues",
Translational Regenerative Medicine,
Eds. Atala A., and Allickson J.,
Elsevier, 1, vol. 1, pp. 127-137, 2015.
Salgado A. J., Oliveira J. M., Martins A., Teixeira F. G., Silva N. A., Neves N. M., Sousa N., and Reis R. L.,
"Tissue Engineering and Regenerative Medicine: Past, Present, and Future",
Tissue Engineering of the Peripheral Nerve: Stem Cells and Regeneration Promoting FactorsAcademic Press,
Eds. Geuna S., Perroteau I., Tos P., and Battiston B.,
Academic Press, vol. 108, pp. 1-33, doi:
10.1016/B978-0-12-410499-0.00001-0, 2013.
Costa R. R., and Mano J. F.,
"Layer-by-layer self-assembly techniques for nanostructured devices in tissue engineering",
Nanomaterials in tissue engineering: characterization, fabrication and applications,
Eds. Gaharwar A. K., Sant S., Hancock M. J., and Hacking S. A.,
Woodhead Publishing Limited, pp. 88-118, doi:
10.1533/9780857097231.1.88, 2013.
Costa R. R., Martín L., Mano J. F., and Rodríguez-Cabello J. C.,
"Elastin-Like Macromolecules",
Biomimetic Approaches for Biomaterials Development,
Eds. Mano J. F.,
WILEY-VCH, pp. 93-116, doi:
10.1002/9783527652273.ch5, 2012.
Invited Journal Paper (1)
Pina S., Ribeiro V. P., Marques C. F., Maia F. R., Silva T. H., Reis R. L., and Oliveira J. M.,
"Scaffolding Strategies for Tissue Engineering and Regenerative Medicine Applications ",
Materials, doi:
10.3390/ma12111824, 2019.
Review Paper (15)
Rodrigues T., Kundu B., Silva-Correia J., Kundu S. C., Oliveira J. M., Reis R. L., and Correlo V. M.,
"Emerging tumor spheroids technologies for 3D in vitro cancer modeling",
Pharmacology & Therapeutics, vol. 184, issue 2018, pp. 201-211, doi:
10.1016/j.pharmthera.2017.10.018, 2017.
López-Cebral R., Silva-Correia J., Reis R. L., Silva T. H., and Oliveira J. M.,
"Peripheral nerve injury: Current challenges, conventional treatment approaches and new trends on biomaterials-based regenerative strategies",
ACS Biomaterials Science & Engineering, vol. 3, issue 12, pp. 3098–3122, doi:
10.1021/acsbiomaterials.7b00655, 2017.
Shavandi A., Silva T. H., Bekhit A. A., and Bekhit A. E. - D. A.,
"Keratin: dissolution, extraction and biomedical application",
Biomaterials Science, vol. 5, pp. 1699-1735, doi:
10.1039/c7bm00411g, 2017.
Ondrésik, M., Maia F. R., da Silva Morais A., Gertrudes A., Bacelar A. H., Correia C., Gonçalves C., Radhouani H., Sousa, R.A., Oliveira J. M., and Reis R. L.,
"Management of knee osteoarthritis. Current status and future trends.",
Biotechnology and Bioengineering, vol. 114, issue 4, pp. 717–739, doi:
10.1002/bit.26182, 2017.
Carvalho M. R., Daniela L., Reis R. L., Correlo V. M., and Oliveira J. M.,
"Evaluating Biomaterial-and Microfluidic-Based 3D Tumor Models",
Trends in Biotechnology, vol. 33, issue 11, pp. 667–678, doi:
10.1016/j.tibtech.2015.09.009, 2015.
Borges J., Rodrigues, L.C., Reis R. L., and Mano J. F.,
"Layer-by-Layer Assembly of Light-Responsive Polymeric Multilayer Systems",
Advanced Functional Materials, vol. 24, issue 36, pp. 5624-5648, doi:
10.1002/adfm.201401050, 2014.
Correia S. I., Pereira H., Silva-Correia J., Niek V. D. C., Espregueira-Mendes J. D., Oliveira J. M., and Reis R. L.,
"Current Concepts: Tissue Engineering and Regenerative Medicine Applications in the Ankle Joint",
Journal of the Royal Society Interface, vol. 11, issue 92, pp. 20130784, doi:
10.1098/rsif.2013.0784, 2013.
Mano J. F., Sousa N., Boesel L. F., Neves N. M., and Reis R. L.,
"Bioinert, biodegradable and injectable polymeric matrix composites for hard tissue replacement: state of the art and recent developments",
Composites Science and Technology, vol. 64, pp. 789–817, 2004.
Invited Review Paper (4)
Mendes B. B., Gómez-Florit M., Babo P. S., Domingues R. M. A., Reis R. L., and Gomes M. E.,
"Blood derivatives awaken in regenerative medicine strategies to modulate wound healing",
Scar Wars, vol. 129, pp. 376-393, doi:
10.1016/j.addr.2017.12.018, 2018.
Invited Lecture (7)
Duarte A. R. C., Santo V. E., Alves A., Silva S. S., Moreira-Silva J., Silva T. H., Marques A. P., Gomes M. E., Sousa R. A., Mano J. F., and Reis R. L.,
"Unleashing the potential of supercritical fluids for polymer processing in tissue engineering and regenerative medicine",
10th International Symposium on Supercritical Fluids, doi:
10.1016/j.supflu.2013.01.004, 2013.
Conference Abstract -ISI Web of Science Indexed (8)
Vieira S., Vial S., Morais A., Carvalho M. R., Reis R. L., and Oliveira J. M.,
"Gellan-gum coated gold nanorods: A new tool for biomedical applications",
Front. Bioeng. Biotechnol. Conference Abstract: 10th World Biomaterials Congress., vol. 4, doi:
10.3389/conf.FBIOE.2016.01.01358, 2016.
Costa-Pinto A. R., Serre-Miranda C., Cerqueira-Rodrigues B., Martins A., Alves da Silva M. L., Correia-Neves M., and Neves N. M.,
"Artificial thymus_ a tissue engineering strategy",
Tissue Engineering Part A, vol. 21, pp. S-1-S-413, doi:
10.1089/ten.tea.2015.5000.abstracts., 2015.
Costa R. R., Custódio C. A., Arias F. J., Rodríguez-Cabello J. C., and Mano J. F.,
"Self-Assembled Microcapsules with Tunable and Sustained Release of Macromolecules for Tissue Engineering",
Journal of Tissue Engineering and Regenerative Medicine, vol. 6, issue S1, pp. 360, doi:
10.1002/term.1586, 2012.
Costa R. R., Arias F. J., Rodríguez-Cabello J. C., and Mano J. F.,
"Temperature-Responsive Microcapsules Prepared by Nanostructured Multilayers of Chitosan and an Elastin-Like Recombinamer for the Controlled Release of Therapeutic Molecules",
The International Journal of Artificial Organs, vol. 34, issue 8, pp. 656-657, doi:
10.5301/IJAO.2011.8701, 2011.
Costa R. R., Custódio C. A., Arias F. J., Rodríguez-Cabello J. C., and Mano J. F.,
"Nanostructured Films Exhibiting Multiple Stimuli Responsive Behavior and Improved Cell Adhesion for Tissue Engineering",
Histology and Histopathology, vol. 26, issue S1, pp. 228, 2011.