Biomaterials, Biodegradables and Biomimetics Research Group

Abstract

Osteoarthritis (OA) is the most common form of arthritis and the most relevant musculoskeletal disorder worldwide. It is considered to be a joint degenerative disease with imbalanced homeostasis. It can potentially affect any joint in the body, but most often the knees, hip, hand and the lower back suffers from OA. Due to the strong functional association of the joint components OA affects all tissues, present in the joint to a certain degree. Because of its wide occurrence, and great impact on the society OA receives a lot of attention in clinical research, although the molecular background of OA remains incompletely understood. The complexity of the joint structure, and the limited knowledge we have on OA sets many obstacles to the development of effective therapies. As of current state there is no cure for OA.

Journal
Regenerative Strategies for the Treatment of Knee Joint Disabilities
Volume
21
Pagination
55-72
Publisher
Springer International Publishing
ISSN
1868-2006
ISBN
978-3-319-44785-8
URL
http://link.springer.com/chapter/10.1007%2F978-3-319-44785-8_4
Keywords
articular acrtilage, Osteoarthritis
Rights
Restricted Access
Peer Reviewed
Yes
Status
published
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