Biomaterials, Biodegradables and Biomimetics Research Group

Review Paper

Bioinert, biodegradable and injectable polymeric matrix composites for hard tissue replacement: state of the art and recent developments

Abstract

The present review paper examines the use of different types of polymeric matrix composites in hard tissue replacement applica- tions.Thereviewpresentstheactualstateoftheartinthefieldsofbioinertcompositesforpermanentapplications,biodegradable matrixcompositesfortemporaryapplicationsandtheemergingareaofinjectablecomposites.Inallcasessomerecentdevelop- mentsarealsodiscussed.Thepaperstartswithanintroductiontolocatethereader.Bone–analoguecompositesarethenextensively discussed.Severalothersystemsbasedonaninertpolymericmatrixaredescribed,focusingontheirproposedapplications.Agreat emphasisisafterwardsgiventobiodegradablematrixsystems.Themostwidelyusedsyntheticbioresorbablesystemsareanalysed andcomparedwithanexampleofnaturalorigindegradablecomposites–starchbasedcomposites.Finally,compositesystemsthat are non-processable by melt based routes and in many cases injectable are discussed in detail, including several recent developments on this emerging area of research.

Journal
Composites Science and Technology
Volume
64
Pagination
789–817
Keywords
Biomaterials, Injection moulding, Mechanicalproperties, Microstructure, Polymer matrix composites
Rights
Open Access
Peer Reviewed
Yes
Status
published
Year of Publication
2004
Date Published
2004-09-01
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