Biomaterials, Biodegradables and Biomimetics Research Group

Book Chapter

Biomimetic strategies incorporating enzymes into CaP coatings mimicking the in vivo environment.

Abstract

Biomimetic calcium phosphate coating (CaP) methodology mimics the natural biomineralization process of bone, which involves two phases: nucleation and growth. In this chapter we present a successful method to coating biodegradable natural-origin materials with biomimetic CaP layer as a strategy to incorporate enzymes with the main aim of controlling and tailoring their degradation over time. This strategy seems to enhance the bone-bonding, osteoconductive, and osteoinductive properties of natural-origin biomaterials that per se do not present these characteristics.

Journal
Biomimetics and Stem cells - Methods in Molecular Biology
Volume
1202
Edition
1
Pagination
111-119
Publisher
Springer
ISBN
978-1-4939-1331-2
URL
http://link.springer.com/protocol/10.1007%2F7651_2013_53
Keywords
Biomimetics, CaP coatings, enzymes, Natural-origin biomaterials
Rights
Restricted Access
Peer Reviewed
Yes
Status
published
Year of Publication
2014
DOI
10.1007/7651_2013_53
Date Published
2014-12-01
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