Functional chitosan microcarriers for selective cell attachment and expansion

last updated: 2014-11-04
TitleFunctional chitosan microcarriers for selective cell attachment and expansion
Publication TypeConference Abstract -ISI Web of Science Indexed
Year of Publication2014
AuthorsCustódio C. A., Cerqueira M. T., Marques A. P., Reis R. L., and Mano J. F.

The success of many stem cell applications in the biomedical field is highly dependent on the development of reliable techniques either for isolation or selection of specific cell populations with a very high yield and purity.1 In this work we propose the use of chitosan microparticles (μPs) to capture a specific cell type based in the concept of antibody-antigen binding. Our goal was to create new biomaterials capable of selecting within a heterotypic cell suspension, a specific sub-population, and supporting subsequent cell expansion. Such system simultaneously allows the selection and acts as a microcarrier for a specific target, thus reducing cell manipulation and time-consumption.

JournalJournal of Tissue Engineering and Regenerative Medicine
Conference NameTermis EU 2014
Date Published2014-06-10
PublisherWILEY-VCH Verlag GmbH & Co.
Conference LocationGenova, Italy
Keywordscell expansion, cell separation, microcarriers
Peer reviewedyes

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