Biomaterials, Biodegradables and Biomimetics Research Group

Book Chapter

Gene Therapy, Growth Factors, Mesenchymal Cells, New Trends and Future Perspective

Abstract

Meniscal tears are common, prevalent intra-articular knee injury and the most frequent cause of orthopedic surgical procedures [1], being a significant risk factor for the development of osteoarthritis (OA) [2]. As widely documented in the previous chapters, tears in the peripheral (vascularized) portion of the meniscus can be repaired using a variety of operative procedures, while those in the central (avascular) area have a poorer healing capacity. Reconstruction of a torn meniscus in this location is challenging, and the long-term effect of allografts on the progression of OA remains uncertain [3].

Journal
Surgery of the Meniscus
Pagination
559-575
Publisher
Springer International Publishing AG
ISBN
978-3-662-49188-
URL
http://link.springer.com/chapter/10.1007/978-3-662-49188-1_58
Keywords
gene therapy, growth factors, Mesenchymal Cells
Rights
Restricted Access
Peer Reviewed
Yes
Status
published
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