Biomaterials, Biodegradables and Biomimetics Research Group

Papers in Scientific Journals

Optical Projection Tomography as a tool for 3D image tissue engineered products based in hydrogels

Abstract

An Optical Projection Tomography (OPT) system was developed and optimized to image 3D tissue engineered products based in hydrogels. We develop pre-reconstruction algorithms to get the best result from the reconstruction procedure, which include correction of the illumination and determination of sample center of rotation (CoR). Existing methods for CoR determination based on the detection of the maximum variance of reconstructed slices failed, so we develop a new CoR search method based in the detection of the variance sharpest local maximum. We show the capabilities of the system to give quantitative information of different types of hydrogels that may be useful in its characterization.

Journal
Biomedical Optics Express
Volume
5
Issue
10
Pagination
3443–3449
Publisher
Optical Society of America
URL
http://www.opticsinfobase.org/boe/abstract.cfm?uri=boe-5-10-3443
Keywords
gellan gum-based hydrogels, Optical projection tomography
Rights
Open Access
Peer Reviewed
Yes
Status
published
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