Approach on chitosan/virgin coconut oil-based emulsion matrices as a platform to design superabsorbent materials

last updated: 2020-11-19
ProjectNature4Health :: publications list
TitleApproach on chitosan/virgin coconut oil-based emulsion matrices as a platform to design superabsorbent materials
Publication TypePapers in Scientific Journals
Year of Publication2020
AuthorsSilva S. S., Rodrigues, L.C., Fernandes E. M., Gomes J. M., Vilas-Boas A., Pirraco R. P., and Reis R. L.
Abstract

The design of innovative pharmaceutical products, able to reach unexplored market niches, requires natural materials use with improved swelling and moisture properties. Herein, chitosan (CHT), a natural polymer, was combined with virgin coconut oil (VCO), a resource extracted from coconut kernels, to develop emulsion-based films for biomedical purposes. The film's properties were tuned by changing VCO concentrations, and the structural, morphological, and physical properties of the films were evaluated. The CHT/VCO-based film morphology showed the presence of VCO droplets at different sizes, both in the surface and inner part. Moreover, the capability to develop CHT/VCO-films as superabsorbent materials was shown. The film extracts cytotoxicity was assessed using human adipose stem cells, and metabolic activity was confirmed. The findings suggest that incorporating a small volume of VCO into the CHT system, superabsorbent materials with the potential to be applied in biomedical devices that require high swelling properties, can be developed.

JournalCarbohydrate polymers
Volume249
Pagination116839
Date Published2020-12-01
PublisherElsevier
ISSN18791344
DOI10.1016/j.carbpol.2020.116839
URLhttps://www.sciencedirect.com/science/article/pii/S0144861720310122
KeywordsBiomaterials, Chitosan, emulsion film, natural polymers, skin diseases, Virgin coconut oil
RightsrestrictedAccess
Peer reviewedyes
Statuspublished

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