Biomaterials, Biodegradables and Biomimetics Research Group

Papers in Scientific Journals

Approach on chitosan/virgin coconut oil-based emulsion matrices as a platform to design superabsorbent materials

Abstract

The design of innovative pharmaceutical products, able to reach unexplored market niches, requires natural materials use with improved swelling and moisture properties. Herein, chitosan (CHT), a natural polymer, was combined with virgin coconut oil (VCO), a resource extracted from coconut kernels, to develop emulsion-based films for biomedical purposes. The film's properties were tuned by changing VCO concentrations, and the structural, morphological, and physical properties of the films were evaluated. The CHT/VCO-based film morphology showed the presence of VCO droplets at different sizes, both in the surface and inner part. Moreover, the capability to develop CHT/VCO-films as superabsorbent materials was shown. The film extracts cytotoxicity was assessed using human adipose stem cells, and metabolic activity was confirmed. The findings suggest that incorporating a small volume of VCO into the CHT system, superabsorbent materials with the potential to be applied in biomedical devices that require high swelling properties, can be developed.

Journal
Carbohydrate polymers
Volume
249
Pagination
116839
Publisher
Elsevier
ISSN
18791344
URL
https://www.sciencedirect.com/science/article/pii/S0144861720310122
Keywords
Biomaterials, Chitosan, emulsion film, natural polymers, skin diseases, Virgin coconut oil
Rights
Restricted Access
Peer Reviewed
Yes
Status
published
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