Cellulose nanocrystals of variable sulfation degrees can sequester specific platelet lysate-derived biomolecules to modulate stem cell response

last updated: 2020-05-25
ProjectMagTendon :: publications list
TitleCellulose nanocrystals of variable sulfation degrees can sequester specific platelet lysate-derived biomolecules to modulate stem cell response
Publication TypePapers in Scientific Journals
Year of Publication2020
AuthorsMendes B. B., Gómez-Florit M., Osório H., Vilaça A., Domingues R. M. A., Reis R. L., and Gomes M. E.
Abstract

The surface chemistry of cellulose nanocrystals was engineered to show variable sulfation degrees, which was exploited to modulate platelet lysate-derived biomolecule sequestration and presentation. The protein coronas developed on CNC surfaces were characterized and it was demonstrated how they promote different signaling effects on human adipose-derived stem cell behavior.

JournalChemical Communications
Date Published2020-05-21
PublisherRoyal Society of Chemistry
ISSN1473-7604
DOI10.1039/D0CC01850C
URLhttps://pubs.rsc.org/en/content/articlelanding/2020/cc/d0cc01850c/unauth#!divAbstract
KeywordsCellulose nanocrystals, Platelet lysate, protein corona
RightsembargoedAccess (1 Year)
Peer reviewedyes
Statuspublished

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