In recent times, the field of tissue engineering and regenerative medicine
(TERM) has considerably increased the extent of therapeutic strategies for
clinical application in orthopedics. However, TERM approaches have its rules and
requirements, in the respect of the biologic response of each tissue and bioactive
agents which need to be considered, respected, and subject of ongoing studies.
Different medical devices/products have been prematurely available on the market
and used in clinics with limited success. However, other therapeutics, when used in
a serious and evidence-based approach, have achieved considerable success, considering
the respect for