The Meniscus in Normal and Osteoarthritic Tissues: Facing the Structure Property Challenges and Current Treatment Trends

last updated: 2019-05-14
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TitleThe Meniscus in Normal and Osteoarthritic Tissues: Facing the Structure Property Challenges and Current Treatment Trends
Publication TypeInvited Review Paper
Year of Publication2019
AuthorsMurphy C. A., Garg A. K., Silva-Correia J., Reis R. L., Oliveira J. M., and Collins M. N.
Abstract

The treatment of meniscus injuries has recently been facing a paradigm shift toward the field of tissue engineering, with the aim of regenerating damaged and diseased menisci as opposed to current treatment techniques. This review focuses on the structure and mechanics associated with the meniscus. The meniscus is defined in terms of its biological structure and composition. Biomechanics of the meniscus are discussed in detail, as an understanding of the mechanics is fundamental for the development of new meniscal treatment strategies. Key meniscal characteristics such as biological function, damage (tears), and disease are critically analyzed. The latest technologies behind meniscal repair and regeneration are assessed.

Book TitleAnnual Review Of Biomedical Engineering
Volume21
Pagination495–521
Date Published2019-04-10
PublisherAnnual Reviews
ISSN1545-4274
DOI10.1146/annurev-bioeng-060418-052547
Keywordsbiomechanics, cartilage, meniscus, Osteoarthritis, repair
RightsrestrictedAccess
Peer reviewedyes
Statuspublished

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