Biomaterials, Biodegradables and Biomimetics Research Group

Invited Review Paper

The Meniscus in Normal and Osteoarthritic Tissues: Facing the Structure Property Challenges and Current Treatment Trends

Abstract

The treatment of meniscus injuries has recently been facing a paradigm shift toward the field of tissue engineering, with the aim of regenerating damaged and diseased menisci as opposed to current treatment techniques. This review focuses on the structure and mechanics associated with the meniscus. The meniscus is defined in terms of its biological structure and composition. Biomechanics of the meniscus are discussed in detail, as an understanding of the mechanics is fundamental for the development of new meniscal treatment strategies. Key meniscal characteristics such as biological function, damage (tears), and disease are critically analyzed. The latest technologies behind meniscal repair and regeneration are assessed.

Journal
Annual Review Of Biomedical Engineering
Volume
21
Pagination
495–521
Publisher
Annual Reviews
ISSN
1545-4274
Keywords
biomechanics, cartilage, meniscus, Osteoarthritis, repair
Rights
Restricted Access
Peer Reviewed
Yes
Status
published
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