Multi-functional micro-/nano-materials for targeted delivery of cells and drugs

last updated: 2021-01-25
ProjectNanoTech4ALS :: publications list
TitleMulti-functional micro-/nano-materials for targeted delivery of cells and drugs
Publication TypeComunication - Oral
Year of Publication2017
AuthorsCarvalho A. L., Silva-Correia J., Reis R. L., and Oliveira J. M.

Central nervous system (CNS) diseases and injuries are one of the most devastating for patients. In particular, Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disorder with no cure. Actually, it is estimated that the number of ALS cases across the globe will increase 69% from 2015 to 2040. So, there is an urgent need on a detailed knowledge of the pathophysiology of CNS disorders, but also for more specific and effective delivery strategies. In this context, we proposed to use a novel nanomedicine approach using targeted cell delivery vehicles to the CSF that can be guided/monitored by MRI. This novel one-package system allows providing a therapeutic effect by control delivery of drugs and cells and monitoring in vivo their biodistribution. Advances in micro-/nano-biomaterials field will provide new opportunities for an effective treatment of neurological diseases.

Conference Name2nd International Conference on Regenerative Medicine in Neurology (ICRMN)
Date Published2017-06-29
Conference LocationOlsztyn, Poland
Keywordsmicro/nano, targeted delivery
Peer reviewedno

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