Biomaterials, Biodegradables and Biomimetics Research Group

Papers in Scientific Journals

Synthesis, mechanical and thermal rheological properties of new gellan gum derivatives

Abstract

New derivatives of gellan gum (GG) were prepared by covalent attachment of octadecylamine (C18- NH2) to polysaccharide backbone via amide linkage by using bis(4-nitrophenyl) carbonate (4-NPBC) as a coupling agent. The effect of the alkyl chain grafted onto hydrophilic backbone of high molecular weight GG was investigated in terms of physicochemical properties and ability of new derivatives to form hydrogels. A series of hydrogels was obtained in solutions with different kind and concentration of ions and their stability and mechanical properties were evaluated. The obtained derivatives resulted soluble at temperature lower than starting GG and physicochemical properties of obtained hydrogels suggested their potential use in biomedical field.

Journal
Internation Journal of biological macromolecules
Volume
98
Pagination
646-653
Publisher
Elsevier
ISSN
0141-8130
Keywords
Chemical modification, Gellan Gum, hydrogel
Rights
Restricted Access
Peer Reviewed
Yes
Status
published
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