megomes | 3B's Research Group in Biomaterials, Biodegradables and Biomimetics

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Gomes M. E., "TENDON REGENERATION: Understanding Tissue Physiology and Development to Engineer Functional Substitutes", TENDON REGENERATION: Understanding Tissue Physiology and Development to Engineer Functional Substitutes, doi:10.1016/B978-0-12-801590-2.01001-2, 2015.

Papers in Scientific Journals (166)

Almeida H., Domingues R. M. A., Mithieux S. M., Pires R. A., Gonçalves A. I., Gómez-Florit M., Reis R. L., Weiss A. S., and Gomes M. E., "Tropoelastin coated tendon biomimetic scaffolds promote stem cell tenogenic commitment and deposition of elastin-rich matrix", Acs Applied Materials & Interfaces, doi:10.1021/acsami.9b04616, 2019.

Costa-Almeida R., Calejo I., Altieri R., Domingues R. M. A., Giordano E., Reis R. L., and Gomes M. E., "Exploring platelet lysate hydrogel-coated suture threads as biofunctional composite living fibers for cell delivery in tissue repair", Biomedical Materials, doi:10.1088/1748-605X/ab0de6, 2019.

Costa-Almeida R., Reis R. L., and Gomes M. E., "Metabolic Disease Epidemics: Emerging Challenges in Regenerative Medicine", Trends In Endocrinology And Metabolism, doi:10.1016/j.tem.2019.01.001, 2019.

Klemm A., Gómez-Florit M., Carvalho P. A., Wachendörfer M., Gomes M. E., Haugen H. J., and Tiainen H., "Grain boundary corrosion in TiO2 bone scaffolds doped with group II cations", Journal Of The European Ceramic Society, vol. 39, issue 4, pp. 1577-1585, doi:10.1016/j.jeurceramsoc.2018.12.055, 2018.

Mendes B. B., Gómez-Florit M., Pires R. A., Domingues R. M. A., Reis R. L., and Gomes M. E., "Human-based fibrillar nanocomposite hydrogels as bioinstructive matrices to tune stem cell behavior", Nanoscale, vol. 10, issue 36, pp. 17388-17401, doi:10.1039/C8NR04273J, 2018.

Calejo I., Costa-Almeida R., Gonçalves A. I., Berdecka D., Reis R. L., and Gomes M. E., "Bi-directional modulation of cellular interactions in an in vitro co-culture model of tendon-to-bone interface", Cell Proliferation, doi:10.1111/cpr.12493, 2018.

Silva C. F., Babo P. S., Gulino M., Costa L., Oliveira J. M., Silva-Correia J., Domingues R. M. A., Reis R. L., and Gomes M. E., "Injectable and tunable hyaluronic acid hydrogels releasing chemotactic and angiogenic growth factors for endodontic regeneration", Acta Biomaterialia, doi:10.1016/j.actbio.2018.07.035, 2018.

Leite A. J., Gonçalves A. I., Rodrigues M. T., Gomes M. E., and Mano J. F., "Strontium-Doped Bioactive Glass Nanoparticles in Osteogenic Commitment", ACS Appl. Mater. Interfaces, vol. 10, issue 27, pp. 23311–23320, doi:10.1021/acsami.8b06154, 2018.

Almeira L. D. F., Babo P. S., Silva C. R., Rodrigues M. T., Hebling J., Reis R. L., and Gomes M. E., "Hyaluronic acid hydrogels incorporating platelet lysate enhance human pulp cell proliferation and differentiation", Journal of Materials Science: Materials in Medicine, vol. 29, issue 6, pp. 88, doi:10.1007/s10856-018-6088-7, 2018.

Miranda M. S., Rodrigues M. T., Domingues R. M. A., Costa R. R., Paz E., Rodríguez-Abreu C., Freitas P., Almeida B. G., Carvalho M. A., Gonçalves C., Ferreira C. M., Torrado E., Reis R. L., Pedrosa J., and Gomes M. E., "Development of Inhalable Superparamagnetic Iron Oxide Nanoparticles (SPIONs) in Microparticulate System for Antituberculosis Drug Delivery", Advanced Healthcare Materials, vol. 7, issue 15, pp. 1800124, doi:10.1002/adhm.201800124, 2018.

Costa-Almeida R., Carvalho D. T. O., Ferreira M. J. S., Pesqueira T., Monici M., van Loon J. J. W. A., Granja P. L., and Gomes M. E., "Continuous exposure to simulated hypergravity induced changes in proliferation, morphology and gene expression of human tendon cells", Stem Cells And Development, vol. 27, issue 12, pp. 858-869, doi:10.1089/scd.2017.0206, 2018.

Gonçalves A. I., Rotherham M., Markides H., Rodrigues M. T., Reis R. L., Gomes M. E., and Haj A. E., "Triggering the activation of Activin A type II receptor in human adipose stem cells towards tenogenic commitment using mechanomagnetic stimulation", Nanomedicine: Nanotechnology, Biology and Medicine, vol. 14, issue 4, pp. 1149-1159, doi:10.1016/j.nano.2018.02.008, 2018.

Pesqueira T., Costa-Almeida R., Mithieux S. M., Babo P. S., Franco A. R., Mendes B. B., Domingues R. M. A., Freitas P., Reis R. L., Gomes M. E., and Weiss A. S., "Engineering magnetically responsive tropoelastin spongy-like hydrogels for soft tissue regeneration", Journal Of Materials Chemistry B, doi:10.1039/C7TB02035J, 2018.

Costa-Almeida R., Franco A. R., Pesqueira T., Oliveira M. B., Babo P. S., Leonor I. B., Mano J. F., Reis R. L., and Gomes M. E., "The effects of platelet lysate patches on the activity of tendon-derived cells", Acta Biomaterialia, doi:10.1016/j.actbio.2018.01.006, 2018.

Costa-Almeida R., Berdecka D., Rodrigues M. T., Reis R. L., and Gomes M. E., "Tendon explant cultures to study the communication between adipose stem cells and native tendon niche", Journal of Cellular Biochemistry, doi:10.1002/jcb.26573, 2018.

Costa-Almeida R., Calejo I., Reis R. L., and Gomes M. E., "Crosstalk between adipose stem cells and tendon cells reveals a temporal regulation of tenogenesis by matrix deposition and remodeling", Journal Of Cellular Physiology, doi:10.1002/jcp.26363, 2017.

Costa-Almeida R., Granja P. L., and Gomes M. E., "Gravity, Tissue Engineering, and the Missing Link", Trends In Biotechnology, doi:10.1016/j.tibtech.2017.10.017, 2017.

Costa-Almeida R., Domingues R. M. A., Fallahi A., Avci H., Yazdi I. K., Akbari M., Reis R. L., Tamayol A., Gomes M. E., and Khademhosseini A., "Cell-laden composite suture threads for repairing damaged tendons", Journal Of Tissue Engineering And Regenerative Medicine, doi:10.1002/term.2605, 2017.

Gonçalves A. I., Rodrigues M. T., and Gomes M. E., "Tissue-Engineered Magnetic Cell Sheet Patches For Advanced Strategies in Tendon Regeneration", Acta Biomaterialia, doi:10.1016/j.actbio.2017.09.014, 2017.

Pesqueira T., Costa-Almeida R., and Gomes M. E., "Uncovering the effect of low-frequency static magnetic field on tendon-derived cells: from mechanosensing to tenogenesis", Scientific Reports, vol. 7, pp. 10948, doi:10.1038/s41598-017-11253-6, 2017.

Sant S., Coutinho D. F., Gaharwar A. K., Neves N. M., Reis R. L., Gomes M. E., and Khademhosseini A., "Self-Assembled Hydrogel Fiber Bundles from Oppositely Charged Polyelectrolytes Mimic Micro-/Nanoscale Hierarchy of Collagen", Adv. Funct. Mater., doi:10.1002/adfm.201606273, 2017.

Mihaila S. M., Resende M., Reis R. L., Gomes M. E., and Marques A. P., "Interactive endothelial phenotype maintenance and osteogenic differentiation of adipose tissue stromal vascular fraction SSEA-4+ -derived cells", Journal of Tissue Engineering and Regenerative Medicine, vol. 11, issue 7, pp. 1998–2013, doi:10.1002/term.2096, 2017.

Laranjeira M., Domingues R. M. A., Costa-Almeida R., Reis R. L., and Gomes M. E., "3D Mimicry of Native-Tissue-Fiber Architecture Guides Tendon-Derived Cells and Adipose Stem Cells into Artificial Tendon Constructs", Small, doi:10.1002/smll.201700689, 2017.

Silva E. D., Babo P. S., Costa-Almeida R., Domingues R. M. A., Mendes B. B., Paz E., Freitas P., Rodrigues M. T., Granja P. L., and Gomes M. E., "Multifunctional magnetic-responsive hydrogels to engineer tendon-to-bone interface", Nanomedicine: Nanotechnology, Biology and Medicine, doi:10.1016/j.nano.2017.06.002, 2017.

Gonçalves A. I., Gershovich P., Rodrigues M. T., Reis R. L., and Gomes M. E., "Human adipose tissue-derived tenomodulin positive subpopulation of stem cells: a promising source of tendon progenitor cells", Journal of Tissue Engineering and Regenerative Medicine, pp. 1-13, doi:10.1002/term.2495, 2017.

Sousa C. P., Lopez-Peña M., Gúzon F. M., De Abreuc H. V., Luís M. R., Viegas C. A., Camassa J., De Azevedo J. T., Cabrita A. S., Reis R. L., Gomes M. E., and Dias I. R., "Evaluation of bone turnover markers and serum minerals variations for predicting fracture healing versus non-union processes in adult sheep as a model for orthopedic research", Injury-international Journal Of The Care Of The Injured, doi:10.1016/j.injury.2017.05.025, 2017.

Neves L. S., Babo P. S., Gonçalves A. I., Costa-Almeida R., Caridade S. G., Mano J. F., Domingues R. M. A., Rodrigues M. T., Reis R. L., and Gomes M. E., "Injectable Hyaluronic Acid Hydrogels Enriched with Platelet Lysate as a Cryostable Off-the-Shelf System for Cell-Based Therapies", Regenerative Engineering and Translational Medicine, vol. 3, issue 2, pp. 53-69 , doi:10.1007/s40883-017-0029-8, 2017.

Costa-Almeida R., Gasperini L., Borges J., Babo P. S., Rodrigues M. T., Mano J. F., Reis R. L., and Gomes M. E., "Microengineered Multicomponent Hydrogel Fibers: Combining Polyelectrolyte Complexation and Microfluidics", ACS Biomaterials Science & Engineering , vol. 3, issue 7, pp. 1322–1331, doi:10.1021/acsbiomaterials.6b00331, 2017.

Neves M. I., Wechsler M. E., Gomes M. E., Reis R. L., Granja P. L., and Peppas N. A., "Molecularly imprinted intelligent scaffolds for tissue engineering applications", Tissue Engineering Part B: Reviews., vol. 23, issue 1, pp. 27-43, doi:10.1089/ten.teb.2016.0202, 2017.

Babo P. S., Pires R. L., Santos L., Franco A. R., Rodrigues F., Leonor I. B., Reis R. L., and Gomes M. E., "Platelet Lysate-Loaded Photo-crosslinkable Hyaluronic Acid Hydrogels for Periodontal Endogenous Regenerative Technology", ACS Biomaterials Science & Engineering, vol. 3, issue 7, pp. 1359-1369, doi:10.1021/acsbiomaterials.6b00508, 2017.

Requicha J. F., Carvalho P. P., Pires M. A., Dias M. I., Reis R. L., Gomes M. E., and Viegas C. A. A., "Evaluation of Canine Adipose-derived Stem Cells in a Healthy Mice Subcutaneous Model", Journal of Stem Cell Research & Therapy, vol. 6, issue 9, doi:10.4172/2157-7633.1000358, 2016.

Costa-Almeida R., Carvalho D. T. O., Ferreira M. J. S., Aresta G., Gomes M. E., van Loon J. J. W. A., Van der Heiden K., and Granja P. L., "Effects of hypergravity on the angiogenic potential of endothelial cells", Journal Of The Royal Society Interface, vol. 13, doi:10.1098/rsif.2016.0688, 2016.

Babo P. S., Cai X., Plachokova A. S., Reis R. L., Jansen J. A., Gomes M. E., and Walboomers X. F., "The Role of a Platelet Lysate-Based Compartmentalized System as a Carrier of Cells and Platelet-Origin Cytokines for Periodontal Tissue Regeneration", Tissue Engineering: part A, doi:10.1089/ten.tea.2016.0226, 2016.

Babo P. S., Carvalho P. P., Santo V. E., Faria S., Gomes M. E., and Reis R. L., "Assessment of bone healing ability of calcium phosphate cements loaded with platelet lysate in rat calvarial defects", Journal Of Biomaterials Applications, doi:10.1177/0885328216669474, 2016.

Babo P. S., Reis R. L., and Gomes M. E., "Production and characterization of hyaluronic acid microparticles for the controlled delivery of growth factors using a spray/dehydration method", Journal Of Biomaterials Applications, doi:10.1177/0885328216669475, 2016.

Babo P. S., Klymov A., teRiet J., Reis R. L., Jansen J. A., Gomes M. E., and Walboomers X. F., "A radially organized multi-patterned device as a diagnostic tool for the screening of topographies in tissue engineering biomaterials", Tissue Engineering: part C, doi:10.1089/ten.tec.2016.0224, 2016.

Babo P. S., Santo V. E., Gomes M. E., and Reis R. L., "Development of an Injectable Calcium Phosphate/Hyaluronic Acid Microparticles System for Platelet Lysate Sustained Delivery Aiming Bone Regeneration", Macromolecular Bioscience, doi:10.1002/mabi.201600141, 2016.

Santo V. E., Babo P. S., Amador M., Correia C., Cunha B., Coutinho D. F., Neves N. M., Mano J. F., Reis R. L., and Gomes M. E., "Engineering enriched microenvironments with gradients of platelet lysate in hydrogel fibers", Biomacromolecules, vol. 17, issue 6, pp. 1985−1997, doi:10.1021/acs.biomac.6b00150, 2016.

Santos L., Silva M., Gonçalves A. I., Pesqueira T., Rodrigues M. T., and Gomes M. E., "In vitro and in vivo assessment of magnetically actuated biomaterials and prospects in tendon healing", Nanomedicine, issue Revolutionising Healthcare, pp. 1, doi:10.2217/nnm-2015-0014, 2016.

Domingues R. M. A., Chiera S., Gershovich P., Motta A., Reis R. L., and Gomes M. E., "Enhancing the Biomechanical Performance of Anisotropic Nanofibrous Scaffolds in Tendon Tissue Engineering: Reinforcement with Cellulose Nanocrystals", Advanced Healthcare Materials, doi:10.1002/adhm.201501048, 2016.

Oliveira S. M., Pirraco R. P., Marques A. P., Santo V. E., Gomes M. E., Reis R. L., and Mano J. F., "Platelet lysate-based pro-angiogenic nanocoatings", Acta Biomaterialia, vol. 32, pp. 129-137, doi:10.1016/j.actbio.2015.12.028, 2016.

Popa E. G., Santo V. E., Rodrigues M. T., and Gomes M. E., "Magnetically-responsive hydrogels for modulation of chondrogenic differentiation", Polymers, vol. 8, issue 2, pp. 28, doi:10.3390/polym8020028, 2016.

Gonçalves A. I., Rodrigues M. T., Carvalho P. P., Bañobre-López M., Paz E., Freitas P., and Gomes M. E., "Exploring the Potential of Starch/Polycaprolactone Aligned Magnetic Responsive Scaffolds for Tendon Regeneration", Advanced Healthcare Materials, vol. 5, issue 2, pp. 213-222, doi:10.1002/adhm.201500623, 2015.

Santo V. E., Ratanavaraporn J., Sato K., Gomes M. E., Mano J. F., Reis R. L., and Tabata Y., "Cell engineering by the internalization of bioinstructive micelles for enhanced bone regeneration", Nanomedicine, vol. 10, issue 11, pp. 1707-1721, doi:10.2217/nnm.15.11 , 2015.

Domingues R. M. A., Silva M., Gershovich P., Betta S., Babo P. S., Caridade S. G., Mano J. F., Motta A., Reis R. L., and Gomes M. E., "Development of Injectable Hyaluronic Acid/Cellulose Nanocrystals Bionanocomposite Hydrogels for Tissue Engineering Applications", Bioconjugate Chemistry, doi:10.1021/acs.bioconjchem.5b00209, 2015.

Lima J., Gonçalves A. I., Rodrigues M. T., Reis R. L., and Gomes M. E., "The effect of magnetic stimulation on the osteogenic and chondrogenic differentiation of human stem cells derived from the adipose tissue (hASCs)", Journal of Magnetism and Magnetic Materials , vol. 393, pp. 526–536, doi:10.1016/j.jmmm.2015.05.087 , 2015.

Rodrigues A. I., Oliveira M. B., Mano J. F., Gomes M. E., Reis R. L., and Leonor I. B., "Combinatorial effect of silicon and calcium release from starch-based scaffolds on osteogenic differentiation of human adipose stem cells", ACS Biomaterials Science & Engineering, vol. 1, issue 9, pp. 760-770, doi:10.1021/acsbiomaterials.5b00113, 2015.

Popa E. G., Caridade S. G., Mano J. F., Reis R. L., and Gomes M. E., "Chondrogenic potential of injectable κ-carrageenan hydrogel with encapsulated adipose stem cells for cartilage tissue-engineering applications", Journal of Tissue Engineering and Regenerative Medicine, vol. 9, issue 5, pp. 550-563, doi:10.1002/term.1683, 2015.

Costa P. F., Hutmacher D. W., Theodoropoulos C., Gomes M. E., Reis R. L., and Vaquette C., "Additively manufactured device for dynamic culture of large arrays of 3D tissue engineered constructs", Advanced Healthcare Materials, vol. 4, issue 6, pp. 864-873, doi:10.1002/adhm.201400591, 2015.

Santo V. E., Popa E. G., Mano J. F., Gomes M. E., and Reis R. L., "Natural assembly of platelet lysate-loaded nanocarriers into enriched 3D hydrogels for cartilage regeneration", Acta Biomaterialia, doi:10.1016/j.actbio.2015.03.015, 2015.

Khang G., Lee S. K., Kim H. N., Silva-Correia J., Gomes M. E., Viegas C. A. A., Dias I. R., Oliveira J. M., and Reis R. L., "Biological evaluation of intervertebral disc cells in different formulations of gellan gum-based hydrogels", Journal of Tissue Engineering and Regenerative Medicine, vol. 9, issue 3, pp. 265-275 , doi:10.1002/term.1625, 2015.

Oliveira S. M., Santo V. E., Gomes M. E., Reis R. L., and Mano J. F., "Layer-by-Layer Assembled Cell Instructive Nanocoatings containing Platelet Lysate", Biomaterials, vol. 48, pp. 56-65, doi:10.1016/j.biomaterials.2015.01.020, 2015.

Requicha J. F., Viegas C. A., Muñoz F., Azevedo J. M., Leonor I. B., Reis R. L., and Gomes M. E., "A Tissue Engineering Approach for Periodontal Regeneration Based on a Biodegradable Double-Layer Scaffold and Adipose-Derived Stem Cells", Tissue Engineering: Part A, vol. 20, pp. 17-18, doi:10.1089/ten.tea.2013.0360, 2014.

Mihaila S. M., Gaharwar A. K., Reis R. L., Khademhosseini A., Marques A. P., and Gomes M. E., "The osteogenic differentiation of SSEA-4 sub-population of human adipose derived stem cells using silicate nanoplatelets", Biomaterials , vol. 35, issue 33, pp. 9087-99, doi: 10.1016/j.biomaterials.2014.07.052, 2014.

Mihaila S. M., Popa E. G., Reis R. L., Marques A. P., and Gomes M. E., "Fabrication of endothelial cell-laden carrageenan microfibers for microvascularized bone tissue engineering applications", Biomacromolecules [Epub ahead of print], doi:10.1021/bm500036a, 2014.

Rodrigues M. T., Leonor I. B., Gröena N., Viegas C. A., Dias I. R., Caridade S. G., Mano J. F., Gomes M. E., and Reis R. L., "Bone marrow stromal cells on a three-dimensional bioactive fiber mesh undergo osteogenic differentiation in the absence of osteogenic media supplements: The effect of silanol groups", Acta Biomaterialia, vol. 10, issue 10, pp. 4175-4185, doi:10.1016/j.actbio.2014.05.026, 2014.

Costa P. F., Vaquette C., Baldwin J., Chhaya M., Gomes M. E., Reis R. L., Theodoropoulos C., and Hutmacher D. W., "Biofabrication of customized bone grafts by combination of additive manufacturing and bioreactor knowhow", Biofabrication, vol. 6, pp. 1-11, doi:10.1088/1758-5082/6/3/035006, 2014.

Gaharwar A. K., Mihaila S. M., Kulkarni A. A., Patel A., Di Luca A., Reis R. L., Gomes M. E., van Blitterswijk C., Moroni L., and Khademhosseini A., "Amphiphilic beads as depots for sustained drug release integrated into fibrillar scaffold", Journal of Controlled Release , vol. 187, pp. 66-73, doi: 10.1016/j.jconrel.2014.04.035, 2014.

Popa E. G., Reis R. L., and Gomes M. E., "Seaweed polysaccharide-based hydrogels used for the regeneration of articular cartilage", Critical Reviews in Biotechnology, vol. 35, issue 3, pp. 1-14, doi:10.3109/07388551.2014.889079, 2014.

Babo P. S., Santo V. E., Duarte A. R. C., Correia C., Costa M. H. G., Mano J. F., Reis R. L., and Gomes M. E., "Platelet lysate membranes as new autologous templates for tissue engineering applications", The Japanese Journal of Inflammation and Regeneration, vol. 34, issue 1, pp. 033 - 044, doi:10.2492/inflammregen.34.033, 2014.

Requicha J. F., Moura T., Leonor I. B., Martins T., Muñoz F., Reis R. L., Gomes M. E., and Viegas C. A., "Evaluation of a starch-based double layer scaffold for bone regeneration in a rat model", Journal of Orthopaedic Research, vol. 32, pp. 904–909 , doi:10.1002/jor.22609, 2014.

Popa E. G., Carvalho P. P., Dias A. F., Santos T. C., Santo V. E., Marques A. P., Viegas C. A., Dias I. R., Gomes M. E., and Reis R. L., "Evaluation of the in vitro and in vivo biocompatibility of carrageenan based hydrogels", Journal of Biomedical Materials Research part A, doi:10.1002/jbm.a.35081, 2014.

Gardel L. S., Afonso M., Frias C., Gomes M. E., and Reis R. L., "Assessing the repair of critical size bone defects performed in a goat tibia model using tissue-engineered constructs cultured in a bidirectional flow perfusion bioreactor", Journal of Biomaterials Applications, vol. 29, issue 2, pp. 172–185, doi:10.1177/0885328213519351, 2014.

Requicha J. F., Viegas C. A., Muñoz F., Reis R. L., and Gomes M. E., "Periodontal Tissue Engineering Strategies Based on Nonoral Stem Cells", The Anatomical Record, vol. 297, issue 1, pp. 6-15, doi:10.1002/ar.22797, 2014.

Sousa C. P., Azevedo J. T., Reis R. L., Gomes M. E., and Dias I. R., "Short-term variability in biomarkers of bone metabolism in sheep.", Lab Animal, vol. 43, issue 1, pp. 21-26, doi:10.1038/laban.418, 2014.

Gonçalves A. I., Rodrigues M. T., Lee S. J., Atala A., Yoo J., Reis R. L., and Gomes M. E., "Understanding the Role of Growth Factors in Modulating Stem Cell Tenogenesis", PlosOne, vol. 8, issue 12, pp. 1-10, doi:10.1371/journal.pone.0083734, 2013.

Sousa C. P., Azevedo J. T., Silva A. M., Viegas C. A., Reis R. L., Gomes M. E., and Dias I. R., "Serum total and bone alkaline phosphatase levels and their correlation with serum minerals over the lifespan of sheep.", Acta Vet Hung, 2013.

Sousa C. P., Azevedo J. T., Silva A. M., Viegas C. A., Reis R. L., Gomes M. E., and Dias I. R., "Serum total and bone alkaline phosphatase levels and their correlation with serum minerals over the lifespan of sheep. Acta Veterinaria Hungarica", Acta Veterinaria Hungarica, vol. 62, issue 2, pp. 205-214, doi:10.1556/AVet.2013.049, 2013.

Custódio C. A., Santo V. E., Oliveira M. B., Gomes M. E., Reis R. L., and Mano J. F., "Functionalized Microparticles Producing Scaffolds in Combination with Cells", Advanced Functional Materials, vol. 24, issue 10, pp. 1391-1400, doi:10.1002/adfm.201301516, 2013.

Carvalho P. P., Leonor I. B., Smith B. J., Dias I. R., Reis R. L., Gimble J. M., and Gomes M. E., "Undifferentiated human adipose-derived stromal/stem cells loaded onto wet-spun starch-polycaprolactone scaffolds enhance bone regeneration: Nude mice calvarial defect in vivo study", Journal of Biomedical Materials and Research - Part A, pp. [Epub ahead of print], doi:DOI: 10.1002/jbm.a.34983, 2013.

Gardel L. S., Serra L. A., Reis R. L., and Gomes M. E., "Use of Perfusion Bioreactors and Large Animal Models for Long Bone Tissue Engineering.", Tissue Engineering Part B: Reviews, pp. 1-21, doi:10.1089/ten.teb.2013.0010, 2013.

Rada T., Carvalho P. P., Santos T. C., Castro A. G., Reis R. L., and Gomes M. E., "Chondrogenic Potential of Two hASCs Subpopulations Loaded onto Gellan Gum Hydrogel Evaluated in a Nude Mice Model", Curr Stem Cell Res Ther. 2013 Jun 10. [Epub ahead of print], vol. 8, issue 5, pp. 357-364, doi:10.2174/1574888X113089990049 , 2013.

Rodrigues M. T., Reis R. L., and Gomes M. E., "Engineering tendon and ligament tissues: present developments towards successful clinical products", Journal of Tissue Engineering and Regenerative Medicine, vol. 7, issue 9, pp. 673-686, doi:10.1002/term.1459, 2013.

Requicha J. F., Viegas C. A., Hede S., Leonor I. B., Reis R. L., and Gomes M. E., "Design and characterization of a biodegradable double-layer scaffold aimed at periodontal tissue-engineering applications", Journal of Tissue Engineering and Regenerative Medicine, doi:10.1002/term.1816, 2013.

Silva S. S., Popa E. G., Gomes M. E., Oliveira M. B., Nayak S., Bano S., Mano J. F., Kundu S. C., and Reis R. L., "Silk hydrogels from non-mulberry and mulberry silkworm cocoons processed with ionic liquids", Acta Biomaterialia, vol. 9, issue 11, pp. 8972-8982, doi:10.1016/j.actbio.2013.06.044, 2013.

Santo V. E., Gomes M. E., Mano J. F., and Reis R. L., "Controlled Release Strategies for Bone, Cartilage, and Osteochondral Engineering—Part II: Challenges on the Evolution from Single to Multiple Bioactive Factor Delivery", Tissue Engineering: Part B, vol. 19, issue 4, pp. 327-352, doi:10.1089/ten.TEB.2012.0727, 2013.

Gardel L. S., Correia-Gomes C., Serra L. A., Gomes M. E., and Reis R. L., "A Novel Bidirectional Continuous Perfusion Bioreactor for the culture of large sized bone tissue engineered constructs.", J Biomed Mater Res Part B: Appl Biomater, doi:10.1002/jbm.b.32955, 2013.

Gaharwar A. K., Mihaila S. M., Swami A., Patel A., Sant A., Reis R. L., Marques A. P., Gomes M. E., and Khademhosseini A., "Bioactive Silicate Nanoplatelets for Osteogenic Differentiation of Human Mesenchymal Stem Cells.", Advanced Materials, doi:10.1002/adma.201300584, 2013.

Link D. P., Gardel L. S., Correlo V. M., Gomes M. E., and Reis R. L., "Osteogenic properties of starch poly(e-caprolactone) (SPCL) fiber meshes loaded with osteoblast-like cells in a rat critical-sized cranial defect", Journal of Biomedical Materials Research - Part A, vol. 101, issue 11, pp. 3059-65, doi:10.1002/jbm.a.34614, 2013.

Carvalho P. P., Gimble J. M., Dias I. R., Gomes M. E., and Reis R. L., "Xeno-free enzymatic products for the isolation of human adipose-derived stromal/stem cells", Tissue Eng Part C Methods, vol. 19, issue 6, pp. 473-478, doi:10.1089/ten.tec.2012.0465, 2013.

Leal A. I., Caridade S. G., Ma J., Yu N., Gomes M. E., Reis R. L., Jansen J. A., Walboomers X. F., and Mano J. F., "Asymmetric PDLLA membranes containing Bioglass® for guided tissue Regeneration: characterization and in-vitro biological behavior", Dental Materials , vol. 29, issue 4, pp. 427-436, doi:10.1016/j.dental.2013.01.009, 2013.

Silva S. S., Popa E. G., Gomes M. E., Cerqueira M. T., Marques A. P., Caridade S. G., Teixeira P., Sousa C., Mano J. F., and Reis R. L., "An investigation of the potential application of chitosan/aloe-based membranes for regenerative medicine", Acta Biomaterialia , doi:10.1016/j.actbio.2013.02.027, 2013.

Duarte A. R. C., Santo V. E., Alves A., Silva S. S., Moreira-Silva J., Silva T. H., Marques A. P., Gomes M. E., Sousa R. A., Mano J. F., and Reis R. L., "Unleashing the potential of supercritical fluids for polymer processing in tissue engineering and regenerative medicine", The Journal of Supercritical Fluids, vol. 79, pp. 177-185, doi:10.1016/j.supflu.2013.01.004, 2013.

Mihaila S. M., Gaharwar A. K., Reis R. L., Marques A. P., Gomes M. E., and Khademhosseini A., "Photocrosslinkable Kappa-Carrageenan Hydrogels for Tissue Engineering Applications", Advanced Healthcare Materials, doi:10.1002/adhm.201200317, 2012.

Mihaila S. M., Frias A. M., Pirraco R. P., Rada T., Reis R. L., Gomes M. E., and Marques A. P., "Human Adipose Tissue-Derived SSEA-4 SubPopulation Multi-Differentiation Potential Towards the Endothelial and Osteogenic Lineages", Tissue Engineering part A, vol. 19, issue 1-2, pp. 235-246, doi:10.1089/ten.tea.2012.0092, 2012.

Popa E. G., Rodrigues M. T., Coutinho D. F., Oliveira M. B., Mano J. F., Reis R. L., and Gomes M. E., "Cryopreservation of cell laden natural origin hydrogels for cartilage regeneration strategies", Soft Matter, doi:10.1039/c2sm26846a, 2012.

Rodrigues M. T., Lee B. K., Lee S. J., Gomes M. E., Reis R. L., Atala A., and Yoo J., "The effect of differentiation stage of amniotic fluid stem cells on bone regeneration", Biomaterials , vol. 33, issue 26, pp. 6069–6078, doi:10.1016/j.biomaterials.2012.05.016, 2012.

Rodrigues M. T., Lee S. J., Gomes M. E., Reis R. L., Atala A., and Yoo J., "Amniotic Fluid-derived Stem Cells as a Cell Source for Bone Tissue Engineering", Tissue Engineering , vol. 18, issue 23/24, pp. 2518-2527, doi:10.1089/ten.tea.2011.0672, 2012.

Santo V. E., Duarte A. R. C., Popa E. G., Gomes M. E., Mano J. F., and Reis R. L., "Enhancement of osteogenic differentiation of human adipose derived stem cells by the controlled release of platelet lysates from hybrid scaffolds produced by supercritical fluid foaming", Journal of Controlled Release, vol. 162, issue 1, pp. 19-27, 2012.

Costa P. F., Dias A. F., Reis R. L., and Gomes M. E., "Cryopreservation of Cell/Scaffold Tissue-Engineered Constructs", Tissue Engineering Part C: Methods, vol. 18, issue 11, pp. 852-858, doi:10.1089/ten.tec.2011.0649, 2012.

Mota J., Yu N., Caridade S. G., Luz G. M., Gomes M. E., Reis R. L., Jansen J. A., and Walboomers X. F., "Chitosan/bioactive glass nanoparticle composite membranes for periodontal regeneration", Acta Biomaterialia, vol. 8, issue 11, pp. 4173-4180, doi:10.1016/j.actbio.2012.06.040, 2012.

Rodrigues A. I., Gomes M. E., Leonor I. B., and Reis R. L., "Bioactive starch-based scaffolds and human adipose stem cells are a goodcombination for bone tissue engineering", Acta Biomaterialia, vol. 8, issue 10, pp. 3765–3776, doi:10.1016/j.actbio.2012.05.025, 2012.

Coutinho D. F., Ahari A., Kachouie N., Gomes M. E., Neves N. M., Reis R. L., and Khademhosseini A., "An automated two-phase system for hydrogel microbead production", Biofabrication, vol. 4, issue 3, doi:10.1088/1758-5082/4/3/035003, 2012.

Requicha J. F., Viegas C. A. A., Albuquerque C. M., Azevedo J. M., Reis R. L., and Gomes M. E., "Effect of anatomical origin and cell passage number on the stemness and osteogenic differentiation potential of canine adipose-derived stem cells", Stem Cell Reviews and Reports, vol. 8, issue 4, pp. 1211-1222, doi:10.1007/s12015-012-9397-0, 2012.

Popa E. G., Reis R. L., and Gomes M. E., "Chondrogenic phenotype of different cells encapsulated in κ-carrageenan hydrogels for cartilage regeneration strategies", Biotechnology and Applied Biochemistry, vol. 59, issue 2, pp. 132-141, 2012.

Coutinho D. F., Sant S., Shakiba M., Wang B., Gomes M. E., Neves N. M., Reis R. L., and Khademhosseini A., "Microfabricated photocrosslinkable polyelectrolyte-complex of chitosan and methacrylated gellan gum", Journal of Materials Chemistry, vol. 22, pp. 17262–17271, doi:10.1039/C2JM31374, 2012.

Santo V. E., Gomes M. E., Mano J. F., and Reis R. L., "Chitosan/Chondroitin sulfate nanoparticles for controlled delivery of platelet lysates in bone regenerative medicine", Journal of Tissue Engineering and Regenerative Medicine, 2012.

Rodrigues M. T., Lee S. J., Gomes M. E., Reis R. L., Atala A., and Yoo J., "Bilayered constructs aimed at osteochondral strategies: the influence of media supplements in the osteogenic and chondrogenic differentiation of amniotic fluid-derived stem cells", Acta Biomaterialia, vol. 8, issue 7, pp. 2795-806, 2012.

Santo V. E., Gomes M. E., Mano J. F., and Reis R. L., "Chitosan-chondroitin sulphate nanoparticles for controlled delivery of platelet lysates in bone regenerative medicine", JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, vol. 6, pp. s47-s59, doi:10.1002/term.1519, 2012.

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